Connexin 43 Polyclonal Antibody | E-AB-70097

Connexin 43 Polyclonal Antibody | E-AB-70097 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Cardiovascular, Signal Transduction

Background: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.

Lead Time: 7~10 days

Concentration: 0.53 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:1000-1:2000, IHC 1:300-1:800

Conjugation: Unconjugated

Calculated Molecular Weight: 43 kDa

Observed Molecular Weight: 43 kDa

Clonality: Polyclonal