Description
Collagenase 3 Antibody / MMP13 | F54843-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC-P, WB
Buffer: N/A
Limitation: This Collagenase 3 antibody is available for research use only.
Purity: Purified
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Immunogen: A portion of amino acids 295-324 from the human protein was used as the immunogen for the Collagenase 3 antibody.
Storage: Aliquot the Collagenase 3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
