Collagen VII antibody / COL7A1 | V7688-20UG

Collagen VII antibody / COL7A1 | V7688-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: LH7.2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA, WB, FACS, IF, IHC-P

Buffer: N/A

Limitation: This Collagen VII antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes an epitope located on collagenase digested Type VII collagen (150kDa), i.e. the non-helical carboxyl terminal region of the dimer. Binding is localized at the inferior border of the lamina densa as demonstrated by immunoelectron microscopy. Type VII is also found in the retina, where its function is unknown. It interacts with Laminin 5 and Fibronectin. Collagen VII is a stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.

Immunogen: A recombinant full-length human Collagen VII protein was used as the immunogen for this Collagen VII antibody.

Storage: Store the Collagen VII antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).