Description
CNGB3 Antibody | R36477-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Goat
Clonality: Polyclonal (goat origin)
Species Reactivity: Human
Application: IHC-P, ELISA (peptide)
Buffer: N/A
Limitation: This CNGB3 antibody is available for research use only.
Purity: Antigen affinity
Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. Cyclic nucleotide-gated cation channel beta-3 can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. [UniProt]
Immunogen: Amino acids ESDDKPTEHYYR were used as the immunogen for this CNGB3 antibody.
Storage: Aliquot and store the CNGB3 antibody at -20 °C.
