Description
CLK1, GST-tag | 40196 | Gentaur US, UK & Europe Disrtribition
Category: Kinase-Serine/Threonine/Protein
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: CLK/STY is a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. The phosphorylated serine/arginine-rich (SR) proteins involves in the pre-mRNA processing and releasing through nucleus into nucleoplasm. CLK/STY, which could phosphorylates the specific SR proteins (1), such as ASF/SF2, may directly regulates the activity and compartmentalization of SR splicing factors (2).
Description: Recombinant human CLK1 (a.a. 129-end), with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.
Product Type: Protein
Shippement Condition: -80°C
