CLEC1 Antibody | N1092-100UG

CLEC1 Antibody | N1092-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB

Buffer: 1X PBS, pH 7.4

Limitation: This CLEC1 antibody is available for research use only.

Purity: Protein A purified antibody

Description: CLEC1 is a C-type lectin receptor and part of the ‘Dectin-1 cluster’ subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.

Immunogen: A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.

Storage: Aliquot the CLEC1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.