Claudin 2 Antibody (CLDN2) | F49580-0.4ML

Claudin 2 Antibody (CLDN2) | F49580-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This Claudin 2 antibody is available for research use only.

Purity: Antigen affinity

Description: Claudin-2 is expressed in cation-leaky epithelia such as that of the kidney proximal tubule. Mice that are deficient in the protein have reduced reabsorption of Na+ in the proximal tubule, consistent with a role in paracellular transport. Similar results have been obtained with cultured cells, as overexpression in CLDN2 lacking cells leads to increase of permeability for small cations. Furthermore, CLDN2 has been shown to form paracellular channels for water. [Wiki]

Immunogen: A portion of amino acids 135-164 from the human protein was used as the immunogen for this Claudin 2 antibody.

Storage: Aliquot the Claudin 2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.