CK2a1, GST-tag | 40045

CK2a1, GST-tag | 40045 | Gentaur US, UK & Europe Disrtribition

Category: Kinase-Serine/Threonine/Protein

Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Background: CK2α is a serine-threonine protein kinase whose targets include many critical regulators of cellular growth. It is highly expressed in a lymphopro-liferative disease of cattle and in many human cancers. Overexpression of the CK2 catalytic subunit in lymphocytes of transgenic mice leads to T cell lymphoma (1). The highest CK2α1 activity is found in mouse testicles and brain, followed by spleen, liver, lung, kidney and heart (2).

Description: Recombinant full-length human CK2alpha1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_001895.

Product Type: Protein

Shippement Condition: -80°C