CK-7 Polyclonal Antibody | E-AB-40292

CK-7 Polyclonal Antibody | E-AB-40292 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Signal Transduction

Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT7, also named as cytokeratin 7, is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels, and their neoplasms. KRT7 is marker of epithelial tissues, but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.

Lead Time: 7~10 days

Concentration: 0.85 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Mouse Keratin, type II cytoskeletal 7 protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification: Antigen Affinity Purification

Dilution: WB 1:500-1:2000 IHC 1:100-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 51 kDa

Observed Molecular Weight: 51 kDa

Clonality: Polyclonal