Description
Chromogranin A Polyclonal Antibody | E-AB-40339 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers
Background: Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors), and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Mouse Chromogranin-A protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification: Antigen Affinity Purification
Dilution: WB 1:500-1:1000 IHC 1:100-1:300
Conjugation: Unconjugated
Calculated Molecular Weight: 51 kDa
Observed Molecular Weight: 51 kDa
Clonality: Polyclonal