Chromogranin A Antibody Cocktail | V3140SAF-100UG

Chromogranin A Antibody Cocktail | V3140SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: LK2H10 + PHE5

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: IHC-P

Buffer: N/A

Limitation: This Chromogranin A antibody cocktail is available for research use only.

Purity: Protein G affinity chromatography

Description: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Immunogen: Human pheochromocytoma cells were used as the immunogen for this Chromogranin A antibody cocktail (LK2H10 & PHE5).

Storage: Store the Chromogranin A antibody cocktail at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).