Description
CHK1 Antibody (pS296) | RQ4710 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: FEO-3
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This phospho-Chk1 antibody (pS296) is available for research use only.
Purity: Affinity purified
Description: The protein encoded by CHEK1 belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. [RefSeq]
Immunogen: A synthetic peptide human Chk1 / CHEK1 (surrounding pS296) was used as the immunogen for the phospho-Chk1 antibody (pS296).
Storage: Store the phospho-Chk1 antibody (pS296) at -20 °C.
