CFH Antibody / Complement factor H | F54343-0.4ML

CFH Antibody / Complement factor H | F54343-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC-P, WB, IF

Buffer: N/A

Limitation: This Complement factor H antibody is available for research use only.

Purity: Antigen affinity purified

Description: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Immunogen: A portion of amino acids 751-780 from the human protein was used as the immunogen for the Complement factor H antibody.

Storage: Aliquot the Complement factor H antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.