Description
CDH20 Antibody / Cadherin 20 | F55047-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, FACS, IHC-P
Buffer: N/A
Limitation: This Cadherin 20 antibody is available for research use only.
Purity: Antigen affinity purified
Description: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
Immunogen: A portion of amino acids 111-140 from the human protein was used as the immunogen for the Cadherin 20 antibody.
Storage: Aliquot the Cadherin 20 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
