Description
CDH1 Antibody | F52228-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 813CT11.1.3
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse
Application: IHC, WB, ELISA
Buffer: N/A
Limitation: This CDH1 antibody is available for research use only.
Purity: Purified
Description: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Immunogen: Purified His-tagged protein was used to produced this monoclonal CDH1 antibody.
Storage: Aliquot the CDH1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
