CDC6 Antibody | F49544-0.08ML

CDC6 Antibody | F49544-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This CDC6 antibody is available for research use only.

Purity: Antigen affinity

Description: Human CDC6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Immunogen: A portion of amino acids 32-61 from the human protein was used as the immunogen for this CDC6 antibody.

Storage: Aliquot the CDC6 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.