Description
CDC25A Antibody (pS124) | F54292-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This Phospho-CDC25A antibody is available for research use only.
Purity: Antigen affinity purified
Description: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen: The amino acids surrounding phosphorylated serine 124 from the human protein were used as the immunogen for the phospho-CDC25A antibody.
Storage: Aliquot the phospho-CDC25A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
