CD86 Polyclonal Antibody | E-AB-65859

CD86 Polyclonal Antibody | E-AB-65859 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC, IF

Research Area: Cancer, Immunology, Microbiology, Stem cells

Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human CD86 (NP_787058.4).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 12 kDa/24 kDa/28 kDa/31 kDa/37 kDa

Observed Molecular Weight: 68 kDa/80 kDa

Clonality: N/A