Description
CD79b Antibody | V8930SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: IGB/2940R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG
Species Reactivity: Human
Application: ELISA
Application Details: ELISA: 2-4ug/ml (order BSA-azide free format for coating)
Application Note: Optimal dilution of the CD79b antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Immunogen: A portion of amino acids 29-159 was used as the immunogen for the CD79b antibody.
Storage: Aliquot the CD79b antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Cell surface
