CD79b Antibody | V8930-20UG

CD79b Antibody | V8930-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: IGB/2940R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG

Species Reactivity: Human

Application: ELISA

Application Details: ELISA: 2-4ug/ml (order BSA-azide free format for coating)

Application Note: Optimal dilution of the CD79b antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

Immunogen: A portion of amino acids 29-159 was used as the immunogen for the CD79b antibody.

Storage: Aliquot the CD79b antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cell surface