Description
CD79b Antibody | V3810-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: CDLA79b-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This CD79b antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. [UniProt]
Immunogen: A portion of amino acids 29-159 was used as the immunogen for the CD79b antibody.
Storage: Store the CD79b antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).