Description
CD74 / CLIP Antibody | V2077-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: LN-2
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse
Application: FACS, IF, IHC-P, WB
Buffer: N/A
Limitation: This CD74 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. CD74 antibody stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. antibody to CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
Immunogen: SU-DHL-4 lymphoma cells were used as the immunogen for this CD74 antibody.
Storage: Store the CD74 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
