Description
CD70-CHO Recombinant Cell line | 79510 | Gentaur US, UK & Europe Disrtribition
Category: Immunotherapy/Cell Line
Application: This cell line is useful for CD70 binding assays, flow cytometry, or for screening for CD70 antibodies. Also useful for immune checkpoint co-stimulatory assay when co-cultured with CD27/NF-κB Reporter-Jurkat cell line (BPS Bioscience #79509).
Background: CD70, also known as TNFSF7, is a cytokine which binds to CD27. CD70 is involved in T-cell activation and induces the proliferation of costimulated T-cells. Moreover, TNFSF7 enhances the generation of cytolytic T-cells. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. Diseases associated with CD70 include acute myocarditis, arthritis, and other inflammatory disorders.
Description: Recombinant CHO-K1 cells constitutively expressing human CD70 (also known as Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7, CD27 Ligand, Ki-24 antigen, CD27-L, and CD27LG; GenBank accession #NM_001252).
Product Type: Cell Line
Shippement Condition: -80°C
