CD7 (T-Cell Leukemia Marker)(HuLy-m2), CF594 conjugate, 0.1mg/mL Antibody | BNC941252-100

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SKU:
37-BNC941252-100
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Weight:
1.00 KGS
€418.00
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Description

CD7 (T-Cell Leukemia Marker)(HuLy-m2), CF594 conjugate, 0.1mg/mL Antibody | BNC941252-100| Gentaur Distribution US, UK & Europe

Summary.: Recognizes a protein of 40 kDa, identified as CD7 (Workshop IV; Code T165). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation..

Conjugate: CF594.

Storage Buffer: PBS, 0.1% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: IF (published).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.

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Additional Information

Size:
100 uL
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