Description
CD63 Antibody / LAMP-3 | V8875-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: LAMP3/4949
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA, FACS, IF, IHC-P
Buffer: N/A
Limitation: This CD63 antibody is available for research use only.
Purity: Protein A/G affinity
Description: CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Immunogen: Full-length human CD63 protein was used as the immunogen for the CD63 antibody.
Storage: Aliquot the CD63 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
