Description
CD6 (Negative Marker of T-regulatory Cells)(SPV-L14), 1mg/mL Antibody | BNUM0402-50| Gentaur Distribution US, UK & Europe
Summary.: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease..
Conjugate: Purified, BSA-free.
Storage Buffer: PBS, no BSA, no azide.
Storage Temperature: 35°C to -5°C .
Application: Flow (verified)|Flow, surface (published)|Functional studies (published)|IF (published)|IF (verified).
Stability: Stable at room temperature or 37°C (98°F) for 7 days.
