CD6 Antibody | V2961SAF-100UG

CD6 Antibody | V2961SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: SPV-L14

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse

Application: FACS, IF

Buffer: N/A

Limitation: This CD6 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Immunogen: A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.

Storage: Store the CD6 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).