Description
CD6 Antibody | V2961-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: SPV-L14
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse
Application: FACS, IF
Buffer: N/A
Limitation: This CD6 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Immunogen: A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.
Storage: Store the CD6 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
