Description
CD6 Antibody Cocktail | V2041SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: C6/372 + 3F7B5
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IF, IHC-P
Buffer: N/A
Limitation: This CD6 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular “scavenger receptor cysteine-rich” (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. antibody to CD6 can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Immunogen: Human recombinant CD6 protein (C6/372) and the rheumatoid synovial T cell line ST-1 (3F7B5) were used as the immunogen for this antibody cocktail.
Storage: Store the CD6 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
