CD54 Polyclonal Antibody | E-AB-70046

CD54 Polyclonal Antibody | E-AB-70046 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, IHC, IF

Research Area: Cancer, Cardiovascular, Immunology, Stem Cells

Background: ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues . ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin . It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum .

Lead Time: 7~10 days

Concentration: 0.84 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:1000-1:3000, IHC 1:500-1:1000, IF 1:200-1:800

Conjugation: Unconjugated

Calculated Molecular Weight: 58 kDa

Observed Molecular Weight: 58 kDa

Clonality: Polyclonal