Description
CD54 Polyclonal Antibody | E-AB-14711 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB, IHC, ELISA
Research Area: Cancer, Cardiovascular, Immunology, Stem Cells
Background: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Lead Time: 7~10 days
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human ICAM1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 58 kDa
Observed Molecular Weight: N/A
Clonality: Polyclonal
