CD5 Antibody Cocktail | V3133IHC-7ML

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SKU:
800-V3133IHC-7ML
Weight:
1.20 KGS
€984.00
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Description

CD5 Antibody Cocktail | V3133IHC-7ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Format: Purified

Clone: C5/473 + CD5/54/F6

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Rat

Application: IHC-P

Buffer: N/A

Limitation: This CD5 antibody cocktail is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

Immunogen: Human recombinant protein (C5/473) and a peptide from the intracellular region of human CD5 (CD5/54/F6) were used as the immunogens for this CD5 antibody cocktail.

Storage: Store the CD5 antibody cocktail at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

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Additional Information

Size:
7 mL
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