Description
CD47 Antibody / IAP / Integrin Associated Protein | V9335-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: rCD47/6365
Host: Mouse
Clonality: Recombinant Mouse Monoclonal
Isotype: Mouse IgG1, kappa
Species Reactivity: Human
Application: IHC-P
Application Details: Immunohistochemistry (FFPE): 1-2ug/ml
Application Note: Optimal dilution of the recombinant Integrin Associated Protein antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: This antibody reacts with Ig domain of CD47/Integrin Associated Protein/IAP protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. It plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47/IAP may play a role in membrane transport and/or integrin dependent signal transduction.
Immunogen: Recombinant full-length human protein was used as the immunogen for the recombinant Integrin Associated Protein antibody.
Storage: Aliquot the recombinant Integrin Associated Protein antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Cell surface, cytoplasmic
