Description
CD47 Antibody / IAP / Integrin Associated Protein | V9272SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: CD47/6364R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG
Species Reactivity: Human
Application: IHC-P
Application Details: Immunohistochemistry (FFPE): 1-2ug/ml
Application Note: Optimal dilution of the recombinant CD47 antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. [UniProt]
Immunogen: A portion of amino acids 18-135 from the human protein was used as the immunogen for the recombinant CD47 antibody.
Storage: Aliquot the recombinant CD47 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Cell surface, cytoplasmic
