CD47 Antibody / IAP / Integrin Associated Protein | V9270SAF-100UG

CD47 Antibody / IAP / Integrin Associated Protein | V9270SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: CD47/6362R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: ELISA, IHC-P

Application Details: ELISA (order BSA-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the recombinant CD47 antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Immunogen: A portion of amino acids 18-135 from the human protein was used as the immunogen for the recombinant CD47 antibody.

Storage: Aliquot the recombinant CD47 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cell surface, cytoplasmic