CD47 Antibody / IAP / Integrin Associated Protein | V2069-100UG

CD47 Antibody / IAP / Integrin Associated Protein | V2069-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: B6H12.2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, WB

Buffer: N/A

Limitation: This CD47 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody reacts with the Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is an ~ 50kDa glycoprotein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Immunogen: Intact CD47 purified from placenta was used as the immunogen for this antibody.

Storage: Store the CD47 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).