CD46 Antibody | V8798SAF-100UG

CD46 Antibody | V8798SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: MCP/931

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF

Buffer: N/A

Limitation: This CD46 antibody is available for research use only.

Purity: Protein affinity

Description: CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

Immunogen: Recombinant human CD46 protein was used as the immunogen for the CD46 antibody.

Storage: Aliquot the CD46 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.