Description
CD46 Antibody | RQ5487 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: AEI-3
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: IHC-P, WB
Buffer: N/A
Limitation: This CD46 antibody is available for research use only.
Purity: Affinity purified
Description: The protein encoded by the CD46 gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. [RefSeq]
Immunogen: A synthetic peptide specific to human CD46 was used as the immunogen for the CD46 antibody.
Storage: Store the CD46 antibody at -20 °C.
