CD46 Antibody | RQ5487

CD46 Antibody | RQ5487 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: AEI-3

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: IHC-P, WB

Buffer: N/A

Limitation: This CD46 antibody is available for research use only.

Purity: Affinity purified

Description: The protein encoded by the CD46 gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. [RefSeq]

Immunogen: A synthetic peptide specific to human CD46 was used as the immunogen for the CD46 antibody.

Storage: Store the CD46 antibody at -20 °C.