Description
CD46 Antibody | F48870-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, FACS, IF, WB, ELISA
Buffer: N/A
Limitation: This CD46 antibody is available for research use only.
Purity: Antigen affinity
Description: CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system.
Immunogen: A portion of amino acids 317-343 from the human protein was used as the immunogen for this CD46 antibody.
Storage: Aliquot the CD46 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
