CD44v3 Antibody | V3768-100UG

CD44v3 Antibody | V3768-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: 3G5

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This CD44v3 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. It is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.

Immunogen: An amino acid sequence from the variant 3 domain of CD44 was used as the immunogen for the CD44v3 antibody.

Storage: Store the CD44v3 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).