CD43 Antibody | V7572-100UG

CD43 Antibody | V7572-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: CDLA43-2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, IHC-P, WB

Buffer: N/A

Limitation: This CD43 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). [UniProt]

Immunogen: Recombinant full-length human SPN protein was used as the immunogen for the CD43 antibody.

Storage: Store the CD43 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).