Description
CD43 Antibody | F40339-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 423CT7.9.2
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This CD43 antibody is available for research use only.
Purity: Purified
Description: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) [UniProt]
Immunogen: A portion of amino acids 230-257 from the human protein was used as the immunogen for this CD43 antibody.
Storage: Aliquot the CD43 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
