Description
CD4 Antibody | V8352SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: GK1.5
Host Animal: Rat
Clonality: Monoclonal (rat origin)
Species Reactivity: Mouse
Application: ELISA, Neutralization, FACS, IF
Buffer: N/A
Limitation: This CD4 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
Immunogen: Mouse CTL clone V4 was used as the immunogen for the CD4 antibody.
Storage: Store the CD4 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
