CD38 (Pig) Fluorogenic Assay Kit (Hydrolase Activity) | 78178

CD38 (Pig) Fluorogenic Assay Kit (Hydrolase Activity) | 78178 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Assay Kit

Application: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Background: CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein that functions as an ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. The main enzymatic activity of CD38 is the hydrolysis of NAD. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic ß cells. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.

Description: The Pig CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of porcine CD38 for screening and profiling applications. In addition, the kit includes the CD38 inhibitor apigenin for use as a control inhibitor.

Product Type: Assay Kit

Shippement Condition: -80°C