Description
CD38 (Dog) Inhibitor Screening Assay Kit (Hydrolase Activity) | 78108 | Gentaur US, UK & Europe Disrtribition
Category: Immunotherapy/Assay Kit
Application: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein that functions as an ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. The major enzymatic activity of CD38 is the hydrolysis of NAD. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic ß cells. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.
Description: The Dog CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of canine CD38 for screening and profiling applications.
Product Type: Assay Kit
Shippement Condition: -80°C
