Description
CD31 Antibody / PECAM-1 | V2219CF488-100T | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: CF488 Conjugate
Clone: C31.7
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS
Buffer: N/A
Limitation: This PECAM-1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Immunogen: Human recombinant PECAM-1 / CD31 protein was used as the immunogen for this antibody.
Storage: Store the PECAM-1 antibody at 2-8oC, protected from light.
