Description
CD3 epsilon Antibody | RQ5184 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: COB-3
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Mouse
Application: IHC-P
Buffer: N/A
Limitation: This CD3e antibody is available for research use only.
Purity: Affinity purified
Description: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [RefSeq]
Immunogen: A synthetic peptide specific to mouse CD3 epsilon / CD3E was used as the immunogen for the CD3e antibody.
Storage: Store the CD3e antibody at -20 °C.
