CD26 Antibody | V2480SAF-100UG

CD26 Antibody | V2480SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: 202.36

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Rat

Application: FACS, IF, IHC-F

Buffer: N/A

Limitation: This CD26 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

Immunogen: A human T cell clone was used as the immunogen for the CD26 antibody.

Storage: Store the CD26 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).