Description
CD26(202-36), Biotin conjugate, 0.1mg/mL Antibody | BNCB0888-100| Gentaur Distribution US, UK & Europe
Summary.: Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .
Conjugate: Biotin.
Storage Buffer: PBS, 0.1% BSA, 0.05% azide.
Storage Temperature: 2°C to 8°C.
Application: Flow, surface (published)|Functional studies (published)|IF (published).
Stability: Stable at room temperature or 37°C (98°F) for 7 days.
