CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL Antibody | BNC881796-100

CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF488A conjugate, 0.1mg/mL Antibody | BNC881796-100| Gentaur Distribution US, UK & Europe

Summary.: This antibody recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: CF488A.

Storage Buffer: PBS, 0.1% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: Flow (verified)|IF (verified)|WB (verified).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.